GPR174 anticorps (Extracellular) (FITC)

N° du produit ABIN7237657

Cet anticorps anti-GPR174 est un anticorps Lapin Polyclonal détectant GPR174 dans FACS et LCI. Adapté pour Humain.

Aperçu rapide pour GPR174 anticorps (Extracellular) (FITC) (ABIN7237657)

Antigène: GPR174 (G Protein-Coupled Receptor 174 (GPR174))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GPR174 est conjugé à/à la FITC

Application: Flow Cytometry (FACS), Live Cell Imaging (LCI)

Détail du produit anti-GPR174 anticorps (FITC)

Épitope: AA 160-175, Extracellular

Fonction: A Rabbit Polyclonal Antibody to GPR174 (extracellular) conjugated to the fluorescent dye FITC

Specificité: 2nd extracellular loop.

Réactivité croisée: Humain, Souris, Rat

Homologie: Human - 15,16 amino acid residues identical, mouse,rat - 13

Attributs du produit: Extracellular, 2nd loop

Purification: Affinity purified on immobilized antigen.

Immunogène:

Immunogen: Synthetic peptide

Immunogen Sequence: (C)DTSGNRTK(S)FVDLPTR, corresponding to amino acid residues 160 - 175 of human GPR174

Isotype: IgG

Information d'application

Indications d'application:

Antigen preadsorption control: 1 μg peptide per 1 μg antibody

Application Dilutions Immunohistochemistry paraffin embedded sections ihc: N/A

Application Dilutions Western blot wb: N/A

Commentaires:

Negative Control: (ABIN7582044)

Blocking Peptide: (ABIN7235384)

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: 15 μL or 50 μL double distilled water (DDW), depending on the sample size.

Concentration: 1 mg/mL

Buffer: PBS pH 7.4, 1 % BSA with 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire:

Storage before reconstitution: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C.

Storage after reconstitution: The reconstituted solution can be stored at 4°C, protected from the light, for up to 1 week. For longer periods, small aliquots should be stored at -20°C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).

Détails sur GPR174

Antigène: GPR174 (G Protein-Coupled Receptor 174 (GPR174))

Autre désignation: GPR174

Sujet: G-protein coupled receptor 174, LYPSR3, GPCR17, FKSG79,GPR174 (LysoPS, LYPSR3), is one of three lysophosphatidyl serine receptors, belonging to the superfamily of G-protein coupled receptors. Lysophospholipids are a diverse group of small, membrane-derived phospholipids that act as extracellular signals1.Activation of GPR174 leads to an increase in cAMP cellular levels, leading to cellular morphological changes, cell to cell adhesion, and delays in cell proliferation2.GPR174 is reported to be a genetic risk locus for Graves disease, an autoimmune disorder that causes hyperthyroidism3 and as a negative regulator of T-cells activation4.

Alternative names: G-protein coupled receptor 174, LYPSR3, GPCR17, FKSG79

ID gène: 84636

NCBI Accession: NM_032553

UniProt: Q9BXC1