ASCL1 anticorps (AA 77-236)
Aperçu rapide pour ASCL1 anticorps (AA 77-236) (ABIN7265373)
Antigène
Voir toutes ASCL1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 77-236
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Fonction
- AscL1 Rabbit pAb
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Séquence
- GGHKSAPKQV KRQRSSSPEL MRCKRRLNFS GFGYSLPQQQ PAAVARRNER ERNRVKLVNL GFATLREHVP NGAANKKMSK VETLRSAVEY IRALQQLLDE HDAVSAAFQA GVLSPTISPN YSNDLNSMAG SPVSSYSSDE GSYDPLSPEE QELLDFTNWF
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Réactivité croisée
- Humain, Souris, Rat
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Attributs du produit
- Polyclonal Antibodies
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Purification
- Affinity purification
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Immunogène
- Recombinant fusion protein containing a sequence corresponding to amino acids 77-236 of human AscL1 (NP_004307.2).
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Isotype
- IgG
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Indications d'application
- WB,1:500 - 1:2000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- ASCL1 (Achaete-Scute Complex Homolog 1 (Drosophila) (ASCL1))
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Autre désignation
- AscL1
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Sujet
- This gene encodes a member of the basic helix-loop-helix (BHLH) family of transcription factors. The protein activates transcription by binding to the E box (5'-CANNTG-3'). Dimerization with other BHLH proteins is required for efficient DNA binding. This protein plays a role in the neuronal commitment and differentiation and in the generation of olfactory and autonomic neurons. Mutations in this gene may contribute to the congenital central hypoventilation syndrome (CCHS) phenotype in rare cases.,ASCL1,ASH1,HASH1,MASH1,bHLHa46,AscL1,Epigenetics & Nuclear Signaling,Transcription Factors,Neuroscience,AscL1
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Poids moléculaire
- 25kDa
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ID gène
- 429
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UniProt
- P50553
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Pathways
- Dopaminergic Neurogenesis
Antigène
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