alpha Actinin 4 anticorps (AA 570-650)

N° du produit ABIN7265400

Cet anticorps anti-alpha Actinin 4 est un anticorps Lapin Polyclonal détectant alpha Actinin 4 dans WB et IF. Adapté pour Humain.

Aperçu rapide pour alpha Actinin 4 anticorps (AA 570-650) (ABIN7265400)

Antigène: alpha Actinin 4 (ACTN4) (Actinin, alpha 4 (ACTN4))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp alpha Actinin 4 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Détail du produit anti-alpha Actinin 4 anticorps

Épitope: AA 570-650

Fonction: α-Actinin-4 Rabbit pAb

Séquence: HDQFKSTLPD ADREREAILA IHKEAQRIAE SNHIKLSGSN PYTTVTPQII NSKWEKVQQL VPKRDHALLE EQSKQQSNEH L

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 570-650 of human alpha-Actinin-4 (NP_004915.2).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IF,1:50 - 1:100

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur alpha Actinin 4

Antigène: alpha Actinin 4 (ACTN4) (Actinin, alpha 4 (ACTN4))

Autre désignation: ACTN4

Sujet: Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a nonmuscle, alpha actinin isoform which is concentrated in the cytoplasm, and thought to be involved in metastatic processes. Mutations in this gene have been associated with focal and segmental glomerulosclerosis.,ACTN4,ACTININ-4,FSGS,FSGS1,Epigenetics & Nuclear Signaling,RNA Binding,Cancer,Invasion and Metastasis,Signal Transduction,Cell Biology & Developmental Biology,Cell Adhesion,Cytoskeleton,Microfilaments,Extracellular Matrix,Endocrine & Metabolism,Immunology & Inflammation,T Cell Receptor Signaling Pathway,ACTN4

Poids moléculaire: 59kDa/79kDa/104kDa

ID gène: 81

UniProt: O43707

Pathways: Proton Transport