ASCC1 anticorps (AA 1-180)
Aperçu rapide pour ASCC1 anticorps (AA 1-180) (ABIN7265402)
Antigène
Voir toutes ASCC1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 1-180
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Fonction
- ASCC1 Rabbit pAb
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Séquence
- MEVLRPQLIR IDGRNYRKNP VQEQTYQHEE DEEDFYQGSM ECADEPCDAY EVEQTPQGFR STLRAPSLLY KHIVGKRGDT RKKIEMETKT SISIPKPGQD GEIVITGQHR NGVISARTRI DVLLDTFRRK QPFTHFLAFF LNEVEVQEGF LRFQEEVLAK CSMDHGVDSS IFQNPKKLHL
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Réactivité croisée
- Humain, Souris, Rat
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Attributs du produit
- Polyclonal Antibodies
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Purification
- Affinity purification
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Immunogène
- Recombinant fusion protein containing a sequence corresponding to amino acids 1-180 of human ASCC1 (NP_001185727.1).
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Isotype
- IgG
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Indications d'application
- WB,1:500 - 1:2000,IF,1:50 - 1:200
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- ASCC1 (Activating Signal Cointegrator 1 Complex Subunit 1 (ASCC1))
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Autre désignation
- ASCC1
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Sujet
- This gene encodes a subunit of the activating signal cointegrator 1 (ASC-1) complex. The ASC-1 complex is a transcriptional coactivator that plays an important role in gene transactivation by multiple transcription factors including activating protein 1 (AP-1), nuclear factor kappa-B (NF-kB) and serum response factor (SRF). The encoded protein contains an N-terminal KH-type RNA-binding motif which is required for AP-1 transactivation by the ASC-1 complex. Mutations in this gene are associated with Barrett esophagus and esophageal adenocarcinoma. Alternatively spliced transcripts encoding multiple isoforms have been observed for this gene.,ASCC1,ASC1p50,CGI-18,SMABF2,p50,Signal Transduction,ASCC1
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Poids moléculaire
- 41kDa/45kDa
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ID gène
- 51008
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UniProt
- Q8N9N2
Antigène
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