ADAM11 anticorps (AA 290-430)

N° du produit ABIN7265433

Cet anticorps anti-ADAM11 est un anticorps Lapin Polyclonal détectant ADAM11 dans WB et IF. Adapté pour Humain.

Aperçu rapide pour ADAM11 anticorps (AA 290-430) (ABIN7265433)

Antigène: ADAM11 (ADAM Metallopeptidase Domain 11 (ADAM11))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ADAM11 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Détail du produit anti-ADAM11 anticorps

Épitope: AA 290-430

Fonction: ADAM11 Rabbit pAb

Séquence: METWADGDKI QVQDDLLETL ARLMVYRREG LPEPSDATHL FSGRTFQSTS SGAAYVGGIC SLSHGGGVNE YGNMGAMAVT LAQTLGQNLG MMWNKHRSSA GDCKCPDIWL GCIMEDTGFY LPRKFSRCSI DEYNQFLQEG G

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 290-430 of human ADAM11 (NP_002381.2).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IF,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur ADAM11

Antigène: ADAM11 (ADAM Metallopeptidase Domain 11 (ADAM11))

Autre désignation: ADAM11

Sujet: This gene encodes a member of the ADAM (a disintegrin and metalloprotease) protein family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The encoded preproprotein is proteolytically processed to generate the mature protease. This gene represents a candidate tumor suppressor gene for human breast cancer based on its location within a minimal region of chromosome 17q21 previously defined by tumor deletion mapping. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.,ADAM11,MDC,Cancer,Invasion and Metastasis,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Extracellular Matrix,ADAM Protein Family,Ubiquitin,ADAM11

Poids moléculaire: 57kDa/83kDa

ID gène: 4185

UniProt: O75078