ADAM15 anticorps
Aperçu rapide pour ADAM15 anticorps (ABIN7265434)
Antigène
Voir toutes ADAM15 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Fonction
- ADAM15 Rabbit mAb
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Réactivité croisée
- Humain, Souris, Rat
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Attributs du produit
- Monoclonal Antibodies
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Purification
- Affinity purification
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Immunogène
- A synthesized peptide derived from human ADAM15
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Isotype
- IgG
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Indications d'application
- WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- ADAM15 (ADAM Metallopeptidase Domain 15 (ADAM15))
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Autre désignation
- ADAM15
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Sujet
- The protein encoded by this gene is a member of the ADAM (a disintegrin and metalloproteinase) protein family. ADAM family members are type I transmembrane glycoproteins known to be involved in cell adhesion and proteolytic ectodomain processing of cytokines and adhesion molecules. This protein contains multiple functional domains including a zinc-binding metalloprotease domain, a disintegrin-like domain, as well as a EGF-like domain. Through its disintegrin-like domain, this protein specifically interacts with the integrin beta chain, beta 3. It also interacts with Src family protein-tyrosine kinases in a phosphorylation-dependent manner, suggesting that this protein may function in cell-cell adhesion as well as in cellular signaling. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008],MDC15,Cancer,Cell Adhesion,Cell Biology & Developmental Biology,Cytoskeleton,Extracellular Matrix,Extracellular Matrix_ADAM Protein Family,Invasion and Metastasis,Signal Transduction,Ubiquitin,ADAM15
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Poids moléculaire
- 90,100kDa
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ID gène
- 8751
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UniProt
- Q13444
Antigène
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