AKT 1/2/3 anticorps (pSer472)
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- Antigène Tous les produits AKT 1/2/3
- AKT 1/2/3
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Épitope
- pSer472
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp AKT 1/2/3 est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Fonction
- Phospho-AKT1-S473+AKT2-S474+AKT3-S472 Rabbit pAb
- Réactivité croisée
- Humain, Souris, Rat
- Attributs du produit
- Phosphorylated Antibodies
- Purification
- Affinity purification
- Immunogène
- A phospho synthetic peptide corresponding to residues surrounding S473/S474/S472 of human AKT1/AKT2/AKT3.
- Isotype
- IgG
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anti-AKT 1/2/3 (AA 401-479) antibody
Reactivité: Humain, Souris, Rat, Boeuf (Vache), Porc WB, FACS, IF (cc), IF (p), ELISA, IHC (p), IHC (fro) Hôte: Lapin Polyclonal unconjugated
anti-AKT 1/2/3 (pSer473) antibodyReactivité: Humain, Souris, Rat, Boeuf (Vache), Poulet, Lapin, Poisson WB, IF (cc), IF (p), ELISA, IHC (p), IHC (fro) Hôte: Lapin Polyclonal unconjugated
anti-AKT 1/2/3 antibodyReactivité: Humain WB, IHC, IF, IP Hôte: Lapin Polyclonal unconjugated
anti-AKT 1/2/3 antibodyReactivité: Humain WB, IHC, IF Hôte: Lapin Monoclonal unconjugated
anti-AKT 1/2/3 (pSer472) antibodyReactivité: Humain, Souris, Rat WB, FACS, IF (cc), IF (p), ELISA, IHC (p), IHC (fro) Hôte: Lapin Polyclonal unconjugated
anti-AKT 1/2/3 (pTyr312), (pTyr315), (pTyr316) antibodyReactivité: Humain WB, IHC, ELISA, IF Hôte: Lapin Polyclonal unconjugated
anti-AKT 1/2/3 (pTyr312), (pTyr315), (pTyr316) antibodyReactivité: Humain, Souris, Rat WB, FACS, IF (cc), IF (p), ELISA, IHC (p), IHC (fro) Hôte: Lapin Polyclonal unconjugated
anti-AKT 1/2/3 (pTyr474) antibodyReactivité: Humain, Souris WB, FACS, IF (cc), IF (p), ELISA, IHC (p), IHC (fro), ICC Hôte: Lapin Polyclonal unconjugated
anti-AKT 1/2/3 (pTyr312), (pTyr315), (pTyr316) antibodyReactivité: Humain, Souris, Rat WB, IHC, IF, ICC Hôte: Lapin Polyclonal unconjugated
anti-AKT 1/2/3 (pSer473) antibodyReactivité: Humain WB, IHC, ELISA Hôte: Lapin Polyclonal unconjugated
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- Indications d'application
- WB,1:500 - 1:2000,IHC,1:50 - 1:200
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- Antigène
- AKT 1/2/3
- Autre désignation
- AKT1/AKT2/AKT3 (AKT 1/2/3 Produits)
- Sujet
- The serine-threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum-starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet-derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3-kinase. In the developing nervous system AKT is a critical mediator of growth factor-induced neuronal survival. Survival factors can suppress apoptosis in a transcription-independent manner by activating the serine/threonine kinase AKT1, which then phosphorylates and inactivates components of the apoptotic machinery. Mutations in this gene have been associated with the Proteus syndrome. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2011],AKT1/AKT2/AKT3,Protein phosphorylation,AKT1/AKT2/AKT3
- Poids moléculaire
- 48kDa/55kDa/51kDa/54kDa
- ID gène
- 207, 208, 10000
- UniProt
- P31749, P31751, Q9Y243
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