BAG3 anticorps
Aperçu rapide pour BAG3 anticorps (ABIN7265850)
Antigène
Voir toutes BAG3 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Fonction
- BAG3 Rabbit mAb
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Réactivité croisée
- Humain, Souris
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Attributs du produit
- Monoclonal Antibodies
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Purification
- Affinity purification
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Immunogène
- A synthesized peptide derived from human BAG3
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Isotype
- IgG
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Indications d'application
- WB,1:500 - 1:2000,IHC,1:50 - 1:200
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- BAG3 (BCL2-Associated Athanogene 3 (BAG3))
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Autre désignation
- BAG3
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Sujet
- BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The protein encoded by this gene contains a WW domain in the N-terminal region and a BAG domain in the C-terminal region. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner. [provided by RefSeq, Jul 2008],BAG-3, BIS, CAIR-1, MFM6,Apoptosis,Apoptosis_Bcl 2 family,Cancer,Cell Biology & Developmental Biology,Endocrine & Metabolism,Invasion and Metastasis,BAG3
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Poids moléculaire
- 80kDa
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ID gène
- 9531
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UniProt
- O95817
Antigène
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