CD276 anticorps (AA 100-200)

N° du produit ABIN7266182

L’anticorps Lapin Polyclonal anti-CD276 a été validé pour WB et IHC (p). Il convient pour détecter CD276 dans des échantillons de Humain.

Aperçu rapide pour CD276 anticorps (AA 100-200) (ABIN7266182)

Antigène: CD276

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CD276 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-CD276 anticorps

Épitope: AA 100-200

Fonction: B7-H3/CD276 Rabbit pAb

Séquence: LAQGNASLRL QRVRVADEGS FTCFVSIRDF GSAAVSLQVA APYSKPSMTL EPNKDLRPGD TVTITCSSYQ GYPEAEVFWQ DGQGVPLTGN VTTSQMANEQ G

Réactivité croisée: Humain, Souris

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: A synthetic peptide corresponding to a sequence within amino acids 100-200 of human B7-H3/CD276 (NP_001019907.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000
IHC-P, 1:50 - 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur CD276

Antigène: CD276

Autre désignation: CD276

Sujet: The protein encoded by this gene belongs to the immunoglobulin superfamily, and thought to participate in the regulation of T-cell-mediated immune response. Studies show that while the transcript of this gene is ubiquitously expressed in normal tissues and solid tumors, the protein is preferentially expressed only in tumor tissues. Additionally, it was observed that the 3' UTR of this transcript contains a target site for miR29 microRNA, and there is an inverse correlation between the expression of this protein and miR29 levels, suggesting regulation of expression of this gene product by miR29. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.,CD276;4Ig-B7-H3;B7-H3;B7H3;B7RP-2,Cancer,Tumor biomarkers,Immunology & Inflammation,CD markers,Stem Cells,Hematopoietic Progenitors,CD276

Poids moléculaire: 33kDa/52kDa/57kDa

ID gène: 80381

UniProt: Q5ZPR3

Pathways: Cancer Immune Checkpoints