CDK1/2/3 (pThr14) anticorps

N° du produit ABIN7266234

Cet anticorps anti-CDK1/2/3 Monoclonal Lapin (ABIN7266234) détecte spécifiquement CDK1/2/3 dans WB. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour CDK1/2/3 (pThr14) anticorps (ABIN7266234)

Antigène: CDK1/2/3

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Inconjugué

Application: Western Blotting (WB)

Détail du produit

Épitope: pThr14

Fonction: Phospho-CDK1/2/3-T14 Rabbit mAb

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Phosphorylated Antibodies

Purification: Affinity purification

Immunogène: A phospho specific peptide corresponding to residues surrounding T14 of human CDK1/2/3

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détail du antigène

Antigène: CDK1/2/3

Autre désignation: CDK1/CDK2/CDK3

Sujet: The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is a catalytic subunit of the highly conserved protein kinase complex known as M-phase promoting factor (MPF), which is essential for G1/S and G2/M phase transitions of eukaryotic cell cycle. Mitotic cyclins stably associate with this protein and function as regulatory subunits. The kinase activity of this protein is controlled by cyclin accumulation and destruction through the cell cycle. The phosphorylation and dephosphorylation of this protein also play important regulatory roles in cell cycle control. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009],CDC2, CDC28A, P34CDC2,Apoptosis,Cell Biology & Developmental Biology,Cell Cycle,Cell Cycle_Centrosome,Cytoskeleton_Microtubules,Epigenetics & Nuclear Signaling,ErbB-HER Signaling Pathway,G protein signaling,G2/M DNA Damage Checkpoint,Immunology & Inflammation,Kinase,Kinase_Serine/threonine kinases,Neurodegenerative Diseases,Neuroscience,Protein phosphorylation,Signal Transduction,CDK1/CDK2/CDK3

Poids moléculaire: 34kDa

ID gène: 983, 1017, 1018

UniProt: P06493, P24941, Q00526