Coronavirus Spike Glycoprotein anticorps
Aperçu rapide pour Coronavirus Spike Glycoprotein anticorps (ABIN7266506)
Antigène
Voir toutes Coronavirus Spike Glycoprotein (CoV S) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Fonction
- SARS-CoV-2 Spike Rabbit pAb
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Réactivité croisée
- SARS Coronavirus-2 (SARS-CoV-2)
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Attributs du produit
- Polyclonal Antibodies
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Purification
- Affinity purification
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Immunogène
- A synthetic peptide of SARS-CoV-2 Spike.
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Isotype
- IgG
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Indications d'application
- ELISA,1:40000-1:160000,WB,1:500 - 1:2000,IF,1:50 - 1:200,IP,1:50 - 1:200
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- Coronavirus Spike Glycoprotein (CoV S)
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Autre désignation
- Spike
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Classe de substances
- Viral Protein
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Sujet
- The spike (S) glycoprotein of coronaviruses contains protrusions that will only bind to certain receptors on the host cell. The spike is essential for both host specificity and viral infectivity. The spike (S) glycoprotein of coronaviruses is known to be essential in the binding of the virus to the host cell at the advent of the infection process. It''s been reported that SARS-CoV-2 (COVID-19 coronavirus, 2019-nCoV) can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. The main functions for the Spike protein are summarized as: Mediate receptor binding and membrane fusion, Defines the range of the hosts and specificity of the virus, Main component to bind with the neutralizing antibody, Key target for vaccine design, Can be transmitted between different hosts through gene recombination or mutation of the receptor binding domain (RBD), leading to a higher mortality rate.,Spike
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ID gène
- 43740568
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UniProt
- P0DTC2
Antigène
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