CRTC2 anticorps (AA 434-693)

N° du produit ABIN7266519

Cet anticorps anti-CRTC2 est un anticorps Lapin Polyclonal détectant CRTC2 dans WB. Adapté pour Humain.

Aperçu rapide pour CRTC2 anticorps (AA 434-693) (ABIN7266519)

Antigène: CRTC2 (CREB Regulated Transcription Coactivator 2 (CRTC2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CRTC2 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-CRTC2 anticorps

Épitope: AA 434-693

Fonction: CRTC2 Rabbit pAb

Séquence: PLSLLAGPAD ARRSQQQLPK QFSPTMSPTL SSITQGVPLD TSKLSTDQRL PPYPYSSPSL VLPTQPHTPK SLQQPGLPSQ SCSVQSSGGQ PPGRQSHYGT PYPPGPSGHG QQSYHRPMSD FNLGNLEQFS MESPSASLVL DPPGFSEGPG FLGGEGPMGG PQDPHTFNHQ NLTHCSRHGS GPNIILTGDS SPGFSKEIAA ALAGVPGFEV SAAGLELGLG LEDELRMEPL GLEGLNMLSD PCALLPDPAV EESFRSDRLQ

Réactivité croisée: Humain

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 434-693 of human CRTC2 (NP_859066.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur CRTC2

Antigène: CRTC2 (CREB Regulated Transcription Coactivator 2 (CRTC2))

Autre désignation: CRTC2

Sujet: This gene encodes a member of the transducers of regulated cAMP response element-binding protein activity family of transcription coactivators. These proteins promote the transcription of genes targeted by the cAMP response element-binding protein, and therefore play an important role in many cellular processes. Under basal conditions the encoded protein is phosphorylated by AMP-activated protein kinase or the salt-inducible kinases and is sequestered in the cytoplasm. Upon activation by elevated cAMP or calcium, the encoded protein translocates to the nucleus and increases target gene expression. Single nucleotide polymorphisms in this gene may increase the risk of type 2 diabetes. A pseudogene of this gene is located on the long arm of chromosome 5.,CRTC2,TORC-2,TORC2,Epigenetics & Nuclear Signaling,Nuclear Receptor Signaling,Nuclear hormone receptors,Cancer,Signal Transduction,Endocrine & Metabolism,AMPK Signaling Pathway,Neuroscience,CRTC2

Poids moléculaire: 73kDa

ID gène: 200186

UniProt: Q53ET0

Pathways: AMPK Signaling, Carbohydrate Homeostasis