CHORDC1 anticorps (AA 60-160)
Aperçu rapide pour CHORDC1 anticorps (AA 60-160) (ABIN7266619)
Antigène
Voir toutes CHORDC1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
-
-
Épitope
- AA 60-160
-
Fonction
- CHORDC1 Rabbit pAb
-
Séquence
- TKGRHNSEKP PEPVKPEVKT TEKKELCELK PKFQEHIIQA PKPVEAIKRP SPDEPMTNLE LKISASLKQA LDKLKLSSGN EENKKEEDND EIKIGTSCKN G
-
Réactivité croisée
- Souris
-
Attributs du produit
- Polyclonal Antibodies
-
Purification
- Affinity purification
-
Immunogène
- Recombinant fusion protein containing a sequence corresponding to amino acids 60-160 of human CHORDC1 (NP_036256.2).
-
Isotype
- IgG
-
-
-
-
Indications d'application
- WB,1:500 - 1:2000
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
-
Agent conservateur
- Sodium azide
-
Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Stock
- -20 °C
-
Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
-
-
- CHORDC1 (Cysteine and Histidine-Rich Domain (CHORD)-Containing 1 (CHORDC1))
-
Autre désignation
- CHORDC1
-
Sujet
- Regulates centrosome duplication, probably by inhibiting the kinase activity of ROCK2. Proposed to act as co-chaperone for HSP90. May play a role in the regulation of NOD1 via a HSP90 chaperone complex. In vitro, has intrinsic chaperone activity. This function may be achieved by inhibiting association of ROCK2 with NPM1. Plays a role in ensuring the localization of the tyrosine kinase receptor EGFR to the plasma membrane, and thus ensures the subsequent regulation of EGFR activity and EGF-induced actin cytoskeleton remodeling. Involved in stress response. Prevents tumorigenesis.,CHORDC1,CHP1,Cell Biology & Developmental Biology,Cell Cycle,Centrosome,CHORDC1
-
ID gène
- 26973
-
UniProt
- Q9UHD1
Antigène
-