Cytosolic Arginine Sensor For mTORC1 Subunit 1 (CASTOR1) anticorps
Aperçu rapide pour Cytosolic Arginine Sensor For mTORC1 Subunit 1 (CASTOR1) anticorps (ABIN7266667)
Antigène
Reactivité
Hôte
Clonalité
Conjugué
Application
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Fonction
- CASTOR1 Rabbit pAb
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Réactivité croisée
- Humain, Souris, Rat
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Attributs du produit
- Polyclonal Antibodies
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Purification
- Affinity purification
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Immunogène
- Recombinant protein of human CASTOR1.
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Isotype
- IgG
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Indications d'application
- WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- Cytosolic Arginine Sensor For mTORC1 Subunit 1 (CASTOR1)
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Autre désignation
- CASTOR1
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Sujet
- Functions as an intracellular arginine sensor within the amino acid-sensing branch of the TORC1 signaling pathway. As a homodimer or a heterodimer with CASTOR2, binds and inhibits the GATOR subcomplex GATOR2 and thereby mTORC1. Binding of arginine to CASTOR1 allosterically disrupts the interaction of CASTOR1-containing dimers with GATOR2 which can in turn activate mTORC1 and the TORC1 signaling pathway.,GATSL3,CASTOR1
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Poids moléculaire
- 36kDa
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ID gène
- 652968
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UniProt
- Q8WTX7
Antigène
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