Cytosolic Arginine Sensor For mTORC1 Subunit 1 (CASTOR1) anticorps

N° du produit ABIN7266667

Détail du produit

Antigène: Cytosolic Arginine Sensor For mTORC1 Subunit 1 (CASTOR1)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Application: Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blotting (WB)

Fonction: CASTOR1 Rabbit pAb

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant protein of human CASTOR1.

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détail du antigène

Antigène: Cytosolic Arginine Sensor For mTORC1 Subunit 1 (CASTOR1)

Autre désignation: CASTOR1

Sujet: Functions as an intracellular arginine sensor within the amino acid-sensing branch of the TORC1 signaling pathway. As a homodimer or a heterodimer with CASTOR2, binds and inhibits the GATOR subcomplex GATOR2 and thereby mTORC1. Binding of arginine to CASTOR1 allosterically disrupts the interaction of CASTOR1-containing dimers with GATOR2 which can in turn activate mTORC1 and the TORC1 signaling pathway.,GATSL3,CASTOR1

Poids moléculaire: 36kDa

ID gène: 652968

UniProt: Q8WTX7