DUSP2 anticorps (AA 150-250)

N° du produit ABIN7266847

Cet anticorps Lapin Polyclonal détecte spécifiquement DUSP2 dans WB. Il présente une réactivité envers Humain.

Aperçu rapide pour DUSP2 anticorps (AA 150-250) (ABIN7266847)

Antigène: DUSP2 (Dual Specificity Phosphatase 2 (DUSP2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DUSP2 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-DUSP2 anticorps

Épitope: AA 150-250

Fonction: DUSP2 Rabbit pAb

Séquence: ALPPTGDKTS RSDSRAPVYD QGGPVEILPY LFLGSCSHSS DLQGLQACGI TAVLNVSASC PNHFEGLFRY KSIPVEDNQM VEISAWFQEA IGFIDWVKNS G

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: A synthetic peptide corresponding to a sequence within amino acids 150-250 of human DUSP2 (NP_004409.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur DUSP2

Antigène: DUSP2 (Dual Specificity Phosphatase 2 (DUSP2))

Autre désignation: DUSP2

Sujet: The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates ERK1 and ERK2, is predominantly expressed in hematopoietic tissues, and is localized in the nucleus.,DUSP2,PAC-1,PAC1,Epigenetics & Nuclear Signaling,Cancer,Tumor suppressors,p53 pathway,Signal Transduction,Cell Biology & Developmental Biology,Apoptosis,Cell Cycle,Endocrine & Metabolism,DUSP2

Poids moléculaire: 34kDa

ID gène: 1844

UniProt: Q05923