Dysferlin anticorps

N° du produit ABIN7266868

Détail du produit anti-Dysferlin anticorps

Antigène: Dysferlin (DYSF)

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp Dysferlin est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Fonction: Dysferlin (Romeo) Rabbit mAb

Réactivité croisée: Humain, Souris

Attributs du produit: Monoclonal Antibodies

Purification: Affinity purification

Immunogène: A synthesized peptide derived from human Dysferlin (Romeo)

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur Dysferlin

Antigène: Dysferlin (DYSF)

Autre désignation: DYSF (DYSF Produits)

Synonymes: anticorps DYSF, anticorps fb73b05, anticorps wu:fb73b05, anticorps si:rp71-50c18.1, anticorps DKFZp459E1226, anticorps 2310004N10Rik, anticorps AI604795, anticorps D6Pas3, anticorps mFLJ00175, anticorps FER1L1, anticorps LGMD2B, anticorps MMD1, anticorps dysferlin, anticorps dysferlin, limb girdle muscular dystrophy 2B (autosomal recessive), anticorps myoferlin, anticorps DYSF, anticorps dysf, anticorps LOC589501, anticorps Dysf

Sujet: The protein encoded by this gene belongs to the ferlin family and is a skeletal muscle protein found associated with the sarcolemma. It is involved in muscle contraction and contains C2 domains that play a role in calcium-mediated membrane fusion events, suggesting that it may be involved in membrane regeneration and repair. In addition, the protein encoded by this gene binds caveolin-3, a skeletal muscle membrane protein which is important in the formation of caveolae. Specific mutations in this gene have been shown to cause autosomal recessive limb girdle muscular dystrophy type 2B (LGMD2B) as well as Miyoshi myopathy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2008],FER1L1, LGMD2B, MMD1,Cell Biology & Developmental Biology,DYSF

Poids moléculaire: 280kDa

ID gène: 8291

UniProt: O75923