E2F5 anticorps (AA 197-346)

N° du produit ABIN7266878

L’anticorps Lapin Polyclonal anti-E2F5 a été validé pour WB. Il convient pour détecter E2F5 dans des échantillons de Humain.

Aperçu rapide pour E2F5 anticorps (AA 197-346) (ABIN7266878)

Antigène: E2F5

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp E2F5 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-E2F5 anticorps

Épitope: AA 197-346

Fonction: E2F5 Rabbit pAb

Séquence: QLEVPIPEMG QNGQKKYQIN LKSHSGPIHV LLINKESSSS KPVVFPVPPP DDLTQPSSQS LTPVTPQKSS MATQNLPEQH VSERSQALQQ TSATDISSAG SISGDIIDEL MSSDVFPLLR LSPTPADDYN FNLDDNEGVC DLFDVQILNY

Réactivité croisée: Humain

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 197-346 of human E2F5 (NP_001942.2).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur E2F5

Antigène: E2F5

Autre désignation: E2F5

Sujet: The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionarily conserved domains that are present in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein is differentially phosphorylated and is expressed in a wide variety of human tissues. It has higher identity to E2F4 than to other family members. Both this protein and E2F4 interact with tumor suppressor proteins p130 and p107, but not with pRB. Alternative splicing results in multiple variants encoding different isoforms.,E2F5,E2F-5,Epigenetics & Nuclear Signaling,Transcription Factors,Signal Transduction,ErbB-HER Signaling Pathway,E2F5

Poids moléculaire: 20kDa/37kDa

ID gène: 1875

UniProt: Q15329