Endoglin anticorps (AA 26-306)
Aperçu rapide pour Endoglin anticorps (AA 26-306) (ABIN7266939)
Antigène
Voir toutes Endoglin (ENG) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
-
-
Épitope
- AA 26-306
-
Fonction
- CD105/Endoglin Rabbit pAb
-
Séquence
- ETVHCDLQPV GPERGEVTYT TSQVSKGCVA QAPNAILEVH VLFLEFPTGP SQLELTLQAS KQNGTWPREV LLVLSVNSSV FLHLQALGIP LHLAYNSSLV TFQEPPGVNT TELPSFPKTQ ILEWAAERGP ITSAAELNDP QSILLRLGQA QGSLSFCMLE ASQDMGRTLE WRPRTPALVR GCHLEGVAGH KEAHILRVLP GHSAGPRTVT VKVELSCAPG DLDAVLILQG PPYVSWLIDA NHNMQIWTTG EYSFKIFPEK NIRGFKLPDT PQGLLGEARM L
-
Réactivité croisée
- Humain, Souris
-
Attributs du produit
- Polyclonal Antibodies
-
Purification
- Affinity purification
-
Immunogène
- Recombinant fusion protein containing a sequence corresponding to amino acids 26-306 of human CD105/Endoglin (NP_001108225.1).
-
Isotype
- IgG
-
-
-
-
Indications d'application
- WB,1:500 - 1:2000
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
-
Agent conservateur
- Sodium azide
-
Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Stock
- -20 °C
-
Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
-
-
- Endoglin (ENG)
-
Autre désignation
- ENG
-
Sujet
- This gene encodes a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds to the beta1 and beta3 peptides with high affinity. Mutations in this gene cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia. This gene may also be involved in preeclampsia and several types of cancer. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.,END,HHT1,ORW1,CD105,ENG,endoglin,Cancer,Tumor biomarkers,Immunology & Inflammation,CD markers,Stem Cells,Endothelial Progenitors,Mesenchymal Stem Cells,Cardiovascular,Cardiovascular Markers,Endothelial Cells,ENG
-
Poids moléculaire
- 67kDa/70kDa
-
ID gène
- 2022
-
UniProt
- P17813
Antigène
-