EIF4G1 anticorps (pSer1108)

N° du produit ABIN7267045

Cet anticorps Lapin Polyclonal détecte spécifiquement EIF4G1 dans WB. Il présente une réactivité envers Humain.

Aperçu rapide pour EIF4G1 anticorps (pSer1108) (ABIN7267045)

Antigène: EIF4G1 (Eukaryotic Translation Initiation Factor 4 Gamma, 1 (EIF4G1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp EIF4G1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-EIF4G1 anticorps

Épitope: pSer1108

Fonction: Phospho-EIF4G1-S1108 Rabbit pAb

Séquence: GGSGA

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Phosphorylated Antibodies

Purification: Affinity purification

Immunogène: A synthetic phosphorylated peptide around S1108 of human EIF4G1 (NP_001181875.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur EIF4G1

Antigène: EIF4G1 (Eukaryotic Translation Initiation Factor 4 Gamma, 1 (EIF4G1))

Autre désignation: EIF4G1

Sujet: The protein encoded by this gene is a component of the multi-subunit protein complex EIF4F. This complex facilitates the recruitment of mRNA to the ribosome, which is a rate-limiting step during the initiation phase of protein synthesis. The recognition of the mRNA cap and the ATP-dependent unwinding of 5'-terminal secondary structure is catalyzed by factors in this complex. The subunit encoded by this gene is a large scaffolding protein that contains binding sites for other members of the EIF4F complex. A domain at its N-terminus can also interact with the poly(A)-binding protein, which may mediate the circularization of mRNA during translation. Alternative splicing results in multiple transcript variants, some of which are derived from alternative promoter usage.,EIF4G1,EIF-4G1,EIF4F,EIF4G,EIF4GI,P220,PARK18,Epigenetics & Nuclear Signaling,RNA Binding,Translation Control,Regulation of eIF4 and p70 S6 Kinase,Signal Transduction,PI3K-Akt Signaling Pathway,Immunology & Inflammation,Akt downstream targets,Protein phosphorylation,EIF4G1

Poids moléculaire: 154kDa/158kDa/166kDa/171kDa/175kDa/176kDa

ID gène: 1981

UniProt: Q04637