FBXO32 anticorps
Aperçu rapide pour FBXO32 anticorps (ABIN7267090)
Antigène
Voir toutes FBXO32 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Fonction
- Fbx32/FBOX32 Rabbit mAb
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Réactivité croisée
- Souris, Rat
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Attributs du produit
- Monoclonal Antibodies
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Purification
- Affinity purification
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Immunogène
- A synthesized peptide derived from human Fbx32/FBOX32
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Isotype
- IgG
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Indications d'application
- WB,1:500 - 1:2000, IHC,1:50 - 1:200
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- FBXO32 (F-Box Protein 32 (FBXO32))
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Autre désignation
- FBXO32
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Sujet
- This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and contains an F-box domain. This protein is highly expressed during muscle atrophy, whereas mice deficient in this gene were found to be resistant to atrophy. This protein is thus a potential drug target for the treatment of muscle atrophy. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jun 2011],Fbx32, MAFbx,Cardiovascular,Cell Biology & Developmental Biology,Heart,Heart_Hypertrophy,Mesenchymal Stem Cells,Stem Cells,Ubiquitin,FBXO32
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Poids moléculaire
- 42kDa
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ID gène
- 114907
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UniProt
- Q969P5
Antigène
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