FAM107A anticorps (AA 1-144)

N° du produit ABIN7267100

L’anticorps Lapin Polyclonal anti-FAM107A a été validé pour WB. Il convient pour détecter FAM107A dans des échantillons de Humain.

Aperçu rapide pour FAM107A anticorps (AA 1-144) (ABIN7267100)

Antigène: FAM107A (Family with Sequence Similarity 107, Member A (FAM107A))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FAM107A est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-FAM107A anticorps

Épitope: AA 1-144

Fonction: FAM107A Rabbit pAb

Séquence: MYSEIQRERA DIGGLMARPE YREWNPELIK PKKLLNPVKA SRSHQELHRE LLMNHRRGLG VDSKPELQRV LEHRRRNQLI KKKKEELEAK RLQCPFEQEL LRRQQRLNQL EKPPEKEEDH APEFIKVREN LRRIATLTSE EREL

Réactivité croisée: Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 1-144 of human FAM107A (NP_009108.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur FAM107A

Antigène: FAM107A (Family with Sequence Similarity 107, Member A (FAM107A))

Autre désignation: FAM107A

Sujet: Stress-inducible actin-binding protein that plays a role in synaptic and cognitive functions by modulating actin filamentous (F-actin dynamics. Mediates polymerization of globular actin to F-actin. Also binds to, stabilizes and bundles F-actin. Involved in synaptic function by regulating neurite outgrowth in an actin-dependent manner and for the acquisition of hippocampus-dependent cognitive function, such as learning and long-term memory (By similarity. Plays a role in the actin and microtubule cytoskeleton organization, negatively regulates focal adhesion (FA assembly promoting malignant glial cell migration in an actin-, microtubule- and MAP1A-dependent manner. Also involved in neuroblastoma G1/S phase cell cycle progression and cell proliferation inhibition by stimulating ubiquitination of NF-kappa-B subunit RELA and NF-kappa-B degradation in a COMMD1- and actin-dependent manner. May play a role in tumor development.,FAM107A,DRR1,TU3A,Cancer,Tumor biomarkers,Cell Biology & Developmental Biology,Cell Cycle,Cell cycle inhibitors,FAM107A

Poids moléculaire: 15kDa/17kDa/20kDa

ID gène: 11170

UniProt: O95990