FAR1 anticorps (AA 1-220)

N° du produit ABIN7267158

Cet anticorps anti-FAR1 est un anticorps Lapin Polyclonal détectant FAR1 dans WB. Adapté pour Humain.

Aperçu rapide pour FAR1 anticorps (AA 1-220) (ABIN7267158)

Antigène: FAR1 (Fatty Acyl CoA Reductase 1 (FAR1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FAR1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-FAR1 anticorps

Épitope: AA 1-220

Fonction: FAR1 Rabbit pAb

Séquence: MVSIPEYYEG KNVLLTGATG FLGKVLLEKL LRSCPKVNSV YVLVRQKAGQ TPQERVEEVL SGKLFDRLRD ENPDFREKII AINSELTQPK LALSEEDKEV IIDSTNIIFH CAATVRFNEN LRDAVQLNVI ATRQLILLAQ QMKNLEVFMH VSTAYAYCNR KHIDEVVYPP PVDPKKLIDS LEWMDDGLVN DITPKLIGDR PNTYIYTKAL AEYVVQQEGA

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 1-220 of human FAR1 (NP_115604.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur FAR1

Antigène: FAR1 (Fatty Acyl CoA Reductase 1 (FAR1))

Autre désignation: FAR1

Sujet: The protein encoded by this gene is required for the reduction of fatty acids to fatty alcohols, a process that is required for the synthesis of monoesters and ether lipids. NADPH is required as a cofactor in this reaction, and 16-18 carbon saturated and unsaturated fatty acids are the preferred substrate. This is a peroxisomal membrane protein, and studies suggest that the N-terminus contains a large catalytic domain located on the outside of the peroxisome, while the C-terminus is exposed to the matrix of the peroxisome. Studies indicate that the regulation of this protein is dependent on plasmalogen levels. Mutations in this gene have been associated with individuals affected by severe intellectual disability, early-onset epilepsy, microcephaly, congenital cataracts, growth retardation, and spasticity (PMID: 25439727). A pseudogene of this gene is located on chromosome 13.,FAR1,MLSTD2,PFCRD,SDR10E1,Cancer,Signal Transduction,Endocrine & Metabolism,Lipid Metabolism,FAR1

Poids moléculaire: 59kDa

ID gène: 84188

UniProt: Q8WVX9