FAR1 anticorps (AA 1-220)
-
- Antigène Voir toutes FAR1 Anticorps
- FAR1 (Fatty Acyl CoA Reductase 1 (FAR1))
-
Épitope
- AA 1-220
-
Reactivité
- Humain
-
Hôte
- Lapin
-
Clonalité
- Polyclonal
-
Conjugué
- Cet anticorp FAR1 est non-conjugé
-
Application
- Western Blotting (WB)
- Fonction
- FAR1 Rabbit pAb
- Séquence
- MVSIPEYYEG KNVLLTGATG FLGKVLLEKL LRSCPKVNSV YVLVRQKAGQ TPQERVEEVL SGKLFDRLRD ENPDFREKII AINSELTQPK LALSEEDKEV IIDSTNIIFH CAATVRFNEN LRDAVQLNVI ATRQLILLAQ QMKNLEVFMH VSTAYAYCNR KHIDEVVYPP PVDPKKLIDS LEWMDDGLVN DITPKLIGDR PNTYIYTKAL AEYVVQQEGA
- Réactivité croisée
- Humain, Souris, Rat
- Attributs du produit
- Polyclonal Antibodies
- Purification
- Affinity purification
- Immunogène
- Recombinant fusion protein containing a sequence corresponding to amino acids 1-220 of human FAR1 (NP_115604.1).
- Isotype
- IgG
- Top Product
- Discover our top product FAR1 Anticorps primaire
-
-
- Indications d'application
- WB,1:500 - 1:2000
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
-
- Antigène
- FAR1 (Fatty Acyl CoA Reductase 1 (FAR1))
- Autre désignation
- FAR1 (FAR1 Produits)
- Synonymes
- anticorps MLSTD2, anticorps SDR10E1, anticorps 2600011M19Rik, anticorps 2900034E22Rik, anticorps 3732409C05Rik, anticorps AI850429, anticorps Mlstd2, anticorps mlstd2, anticorps MQJ16.4, anticorps MQJ16_4, anticorps fatty acid reductase 1, anticorps fatty acyl-CoA reductase 1, anticorps fatty acyl CoA reductase 1, anticorps fatty acyl-CoA reductase 1 L homeolog, anticorps fatty acid reductase 1, anticorps FAR1, anticorps Far1, anticorps far1.L
- Sujet
- The protein encoded by this gene is required for the reduction of fatty acids to fatty alcohols, a process that is required for the synthesis of monoesters and ether lipids. NADPH is required as a cofactor in this reaction, and 16-18 carbon saturated and unsaturated fatty acids are the preferred substrate. This is a peroxisomal membrane protein, and studies suggest that the N-terminus contains a large catalytic domain located on the outside of the peroxisome, while the C-terminus is exposed to the matrix of the peroxisome. Studies indicate that the regulation of this protein is dependent on plasmalogen levels. Mutations in this gene have been associated with individuals affected by severe intellectual disability, early-onset epilepsy, microcephaly, congenital cataracts, growth retardation, and spasticity (PMID: 25439727). A pseudogene of this gene is located on chromosome 13.,FAR1,MLSTD2,PFCRD,SDR10E1,Cancer,Signal Transduction,Endocrine & Metabolism,Lipid Metabolism,FAR1
- Poids moléculaire
- 59kDa
- ID gène
- 84188
- UniProt
- Q8WVX9
-