FIG4 anticorps (AA 608-907)
Aperçu rapide pour FIG4 anticorps (AA 608-907) (ABIN7267203)
Antigène
Voir toutes FIG4 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 608-907
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Fonction
- FIG4 Rabbit pAb
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Séquence
- WELPTDFYLH HKNTMRLLPT RRSYTYWWTP EVIKHLPLPY DEVICAVNLK KLIVKKFHKY EEEIDIHNEF FRPYELSSFD DTFCLAMTSS ARDFMPKTVG IDPSPFTVRK PDETGKSVLG NKSNREEAVL QRKTAASAPP PPSEEAVSSS SEDDSGTDRE EEGSVSQRST PVKMTDAGDS AKVTENVVQP MKELYGINLS DGLSEEDFSI YSRFVQLGQS QHKQDKNSQQ PCSRCSDGVI KLTPISAFSQ DNIYEVQPPR VDRKSTEIFQ AHIQASQGIM QPLGKEDSSM YREYIRNRYL
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Réactivité croisée
- Humain, Souris
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Attributs du produit
- Polyclonal Antibodies
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Purification
- Affinity purification
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Immunogène
- Recombinant fusion protein containing a sequence corresponding to amino acids 608-907 of human FIG4 (NP_055660.1).
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Isotype
- IgG
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Indications d'application
- WB,1:200 - 1:2000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- FIG4 (FIG4 Homolog, SAC1 Lipid Phosphatase Domain Containing (FIG4))
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Autre désignation
- FIG4
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Sujet
- The protein encoded by this gene belongs to the SAC domain-containing protein gene family. The SAC domain, approximately 400 amino acids in length and consisting of seven conserved motifs, has been shown to possess phosphoinositide phosphatase activity. The yeast homolog, Sac1p, is involved in the regulation of various phosphoinositides, and affects diverse cellular functions such as actin cytoskeleton organization, Golgi function, and maintenance of vacuole morphology. Membrane-bound phosphoinositides function as signaling molecules and play a key role in vesicle trafficking in eukaryotic cells. Mutations in this gene have been associated with Charcot-Marie-Tooth disease, type 4J.,FIG4,ALS11,BTOP,CMT4J,KIAA0274,SAC3,YVS,dJ249I4.1,Signal Transduction,Neuroscience,Neurodegenerative Diseases,Other Neurological disorders,Amyotrophic lateral sclerosis-ALS,FIG4
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Poids moléculaire
- 103kDa
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ID gène
- 9896
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UniProt
- Q92562
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Pathways
- Inositol Metabolic Process
Antigène
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