FKBP1A anticorps

N° du produit ABIN7267211

L’anticorps anti-FKBP1A Monoclonal Lapin est utilisé pour la détection de FKBP1A dans des échantillons de Humain. Il a été validé pour WB.

Aperçu rapide pour FKBP1A anticorps (ABIN7267211)

Antigène: FKBP1A (FK506 Binding Protein 1A, 12kDa (FKBP1A))

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp FKBP1A est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-FKBP1A anticorps

Fonction: FKBP12 Rabbit mAb

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Monoclonal Antibodies

Purification: Affinity purification

Immunogène: A synthesized peptide derived from human FKBP12

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur FKBP1A

Antigène: FKBP1A (FK506 Binding Protein 1A, 12kDa (FKBP1A))

Autre désignation: FKBP1A

Sujet: The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. The protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It interacts with several intracellular signal transduction proteins including type I TGF-beta receptor. It also interacts with multiple intracellular calcium release channels, and coordinates multi-protein complex formation of the tetrameric skeletal muscle ryanodine receptor. In mouse, deletion of this homologous gene causes congenital heart disorder known as noncompaction of left ventricular myocardium. Multiple alternatively spliced variants, encoding the same protein, have been identified. The human genome contains five pseudogenes related to this gene, at least one of which is transcribed. [provided by RefSeq, Sep 2008],FKBP-12, FKBP-1A, FKBP1, FKBP12, PKC12, PKCI2, PPIASE,Epigenetic writers and erasers of core Histones,Epigenetic writers and erasers of core Histones_other,Epigenetics & Nuclear Signaling,Immunology & Inflammation,mTOR Signaling Pathway,PI3K-Akt Signaling Pathway,PI3K-Akt Signaling Pathway_Regulator of mTOR complex function,Signal Transduction,TGF-b-Smad Signaling Pathway_Regulator,Translation Control,Translational Control_Regulation of eIF4 and p70 S6 Kinase,FKBP1A

Poids moléculaire: 12kDa

ID gène: 2280

UniProt: P62942

Pathways: Negative Regulation of Transporter Activity, Methionine Biosynthetic Process