FREM1 anticorps (AA 1880-2179)
Aperçu rapide pour FREM1 anticorps (AA 1880-2179) (ABIN7267259)
Antigène
Voir toutes FREM1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 1880-2179
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Fonction
- FREM1 Rabbit pAb
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Séquence
- GSSSSTTSGS FHLERRPLPS SMQLAVIRGD TLRGFDSTDL SQRKLRTRGN GKTVRPSSVY RNGTDIIYNY HGIVSLKLED DSFPTHKRKA KVSIISQPQK TIKVAELPQA DKVESTTDSH FPRQDQLPSF PKNCTLELKG LFHFEEGIQK LYQCNGIAWK AWSPQTKDVE DKSCPAGWHQ HSGYCHILIT EQKGTWNAAA QACREQYLGN LVTVFSRQHM RWLWDIGGRK SFWIGLNDQV HAGHWEWIGG EPVAFTNGRR GPSQRSKLGK SCVLVQRQGK WQTKDCRRAK PHNYVCSRKL
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Réactivité croisée
- Humain, Souris, Rat
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Attributs du produit
- Polyclonal Antibodies
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Purification
- Affinity purification
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Immunogène
- Recombinant fusion protein containing a sequence corresponding to amino acids 1880-2179 of human FREM1 (NP_659403.4).
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Isotype
- IgG
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Indications d'application
- WB,1:500 - 1:2000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- FREM1 (FRAS1 Related Extracellular Matrix 1 (FREM1))
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Autre désignation
- FREM1
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Sujet
- This gene encodes a basement membrane protein that may play a role in craniofacial and renal development. Mutations in this gene have been associated with bifid nose with or without anorectal and renal anomalies. Alternatively spliced transcript variants encoding different isoforms have been described. PubMed ID 19940113 describes one such variant that initiates transcription within a distinct, internal exon, the resulting shorter isoform (named Toll-like/interleukin-1 receptor regulator, TILRR) is suggested to be a co-receptor of the interleukin 1 receptor family and may regulate receptor function and Toll-like receptor/interleukin 1 receptor signal transduction, contributing to the control of inflammatory response activation.,FREM1,BNAR,C9orf143,C9orf145,C9orf154,MOTA,TILRR,TRIGNO2,Cell Biology & Developmental Biology,FREM1
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Poids moléculaire
- 25kDa/42kDa/80kDa/244kDa
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ID gène
- 158326
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UniProt
- Q5H8C1
Antigène
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