anticorps 6030440P17Rik, anticorps 8430406N05Rik, anticorps Gm409, anticorps b2b1562Clo, anticorps my, anticorps ne, anticorps nv1, anticorps RGD1566012, anticorps FRAS1 related extracellular matrix protein 2, anticorps Fras1 related extracellular matrix protein 2, anticorps FREM2, anticorps Frem2
Sujet
This gene encodes an integral membrane protein containing numerous CSPG (chondroitin sulfate proteoglycan element) repeats and Calx-beta domains. The encoded protein localizes to the basement membrane, forming a ternary complex that plays a role in epidermal-dermal interactions. This protein is important for the integrity of skin and renal epithelia. Mutations in this gene are associated with Fraser syndrome.,FREM2,Signal Transduction,Cell Biology & Developmental Biology,Cell Adhesion,Cell Adhesion Molecules,Cytoskeleton,Neuroscience,Calcium Signaling,FREM2