GALR2 anticorps (AA 50-150)

N° du produit ABIN7267335

Cet anticorps anti-GALR2 est un anticorps Lapin Polyclonal détectant GALR2 dans WB. Adapté pour Humain.

Aperçu rapide pour GALR2 anticorps (AA 50-150) (ABIN7267335)

Antigène: GALR2 (Galanin Receptor 2 (GALR2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GALR2 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-GALR2 anticorps

Épitope: AA 50-150

Fonction: GALR2 Rabbit pAb

Séquence: LLRGGQAVST TNLFILNLGV ADLCFILCCV PFQATIYTLD GWVFGSLLCK AVHFLIFLTM HASSFTLAAV SLDRYLAIRY PLHSRELRTP RNALAAIGLI W

Réactivité croisée: Souris

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: A synthetic peptide corresponding to a sequence within amino acids 50-150 of human GALR2 (NP_003848.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur GALR2

Antigène: GALR2 (Galanin Receptor 2 (GALR2))

Autre désignation: GALR2

Sujet: Galanin is an important neuromodulator present in the brain, gastrointestinal system, and hypothalamopituitary axis. It is a 30-amino acid non-C-terminally amidated peptide that potently stimulates growth hormone secretion, inhibits cardiac vagal slowing of heart rate, abolishes sinus arrhythmia, and inhibits postprandial gastrointestinal motility. The actions of galanin are mediated through interaction with specific membrane receptors that are members of the 7-transmembrane family of G protein-coupled receptors. GALR2 interacts with the N-terminal residues of the galanin peptide. The primary signaling mechanism for GALR2 is through the phospholipase C/protein kinase C pathway (via Gq), in contrast to GALR1, which communicates its intracellular signal by inhibition of adenylyl cyclase through Gi. However, it has been demonstrated that GALR2 couples efficiently to both the Gq and Gi proteins to simultaneously activate 2 independent signal transduction pathways. [provided by RefSeq, Jul 2008],GAL2-R,GALNR2,GALR-2,GALR2,Signal Transduction,G protein signaling,G-Protein-Coupled Receptors(GPCR),Endocrine & Metabolism,Neuroscience,GALR2

ID gène: 8811

UniProt: O43603

Pathways: cAMP Metabolic Process, Inositol Metabolic Process, Feeding Behaviour