GSTM5 anticorps (C-Term)

N° du produit ABIN7267445

L’anticorps anti-GSTM5 Polyclonal Lapin est utilisé pour la détection de GSTM5 dans des échantillons de Humain. Il a été validé pour WB et IF.

Aperçu rapide pour GSTM5 anticorps (C-Term) (ABIN7267445)

Antigène: GSTM5 (Glutathione S-Transferase mu 5 (GSTM5))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GSTM5 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Détail du produit anti-GSTM5 anticorps

Épitope: C-Term

Fonction: GSTM5 Rabbit pAb

Séquence: LENQVMDNHM ELVRLCYDPD FEKLKPKYLE ELPEKLKLYS EFLGKRPWFA GDKITFVDFL AYDVLDMKRI FEPKCLDAFL NLKDFISRFE GLKKISAYMK SSQFLRGLLF GKSATWNSK

Réactivité croisée: Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: A synthetic peptide corresponding to a sequence within amino acids 100 to the C-terminus of human GSTM5 (NP_000842.2).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IF,1:50 - 1:100

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur GSTM5

Antigène: GSTM5 (Glutathione S-Transferase mu 5 (GSTM5))

Autre désignation: GSTM5

Sujet: Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. Diversification of these genes has occurred in regions encoding substrate-binding domains, as well as in tissue expression patterns, to accommodate an increasing number of foreign compounds.,GSTM5,GSTM5-5,GTM5,Signal Transduction,Endocrine & Metabolism,Drug metabolism,GSTM5

Poids moléculaire: 25kDa

ID gène: 2949

UniProt: P46439