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Granulin anticorps

L’anticorps Lapin Monoclonal anti-Granulin a été validé pour WB. Il convient pour détecter Granulin dans des échantillons de Humain.
N° du produit ABIN7267505

Aperçu rapide pour Granulin anticorps (ABIN7267505)

Antigène

Voir toutes Granulin (GRN) Anticorps
Granulin (GRN)

Reactivité

  • 53
  • 10
  • 5
  • 1
  • 1
  • 1
  • 1
Humain

Hôte

  • 44
  • 11
  • 5
  • 2
  • 1
Lapin

Clonalité

  • 50
  • 13
Monoclonal

Conjugué

  • 39
  • 7
  • 5
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp Granulin est non-conjugé

Application

  • 55
  • 21
  • 20
  • 13
  • 13
  • 12
  • 10
  • 7
  • 6
  • 3
  • 3
Western Blotting (WB)
  • Fonction

    Granulin Rabbit mAb

     Réactivité croisée

    Humain

    Attributs du produit

    Monoclonal Antibodies

    Purification

    Affinity purification

    Immunogène

    A synthesized peptide derived from human Granulin

    Isotype

    IgG
  • Indications d'application

    WB,1:500 - 1:2000

    Restrictions

    For Research Use only
  • Format

    Liquid

    Buffer

    PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Stock

    -20 °C

    Stockage commentaire

    Store at -20°C. Avoid freeze / thaw cycles.
  • Antigène

    Granulin (GRN)

    Autre désignation

    GRN

    Sujet

    Granulins are a family of secreted, glycosylated peptides that are cleaved from a single precursor protein with 7.5 repeats of a highly conserved 12-cysteine granulin/epithelin motif. The 88 kDa precursor protein, progranulin, is also called proepithelin and PC cell-derived growth factor. Cleavage of the signal peptide produces mature granulin which can be further cleaved into a variety of active, 6 kDa peptides. These smaller cleavage products are named granulin A, granulin B, granulin C, etc. Epithelins 1 and 2 are synonymous with granulins A and B, respectively. Both the peptides and intact granulin protein regulate cell growth. However, different members of the granulin protein family may act as inhibitors, stimulators, or have dual actions on cell growth. Granulin family members are important in normal development, wound healing, and tumorigenesis. [provided by RefSeq, Jul 2008],CLN11, GEP, GP88, PCDGF, PEPI, PGRN,Cancer,Cell Biology & Developmental Biology,Cytokines,Epigenetics & Nuclear Signaling,Growth factors,Immunology & Inflammation,Neurodegenerative Diseases,Neuroscience,RNA Binding,Signal Transduction,GRN

    Poids moléculaire

    55,75kDa

    ID gène

    2896

    UniProt

    P28799
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