HN1 anticorps (AA 1-154)

N° du produit ABIN7267601

L’anticorps Lapin Polyclonal anti-HN1 a été validé pour WB. Il convient pour détecter HN1 dans des échantillons de Humain.

Aperçu rapide pour HN1 anticorps (AA 1-154) (ABIN7267601)

Antigène: HN1 (Hematological and Neurological Expressed 1 (HN1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HN1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-HN1 anticorps

Épitope: AA 1-154

Fonction: HN1 Rabbit pAb

Séquence: MTTTTTFKGV DPNSRNSSRV LRPPGGGSNF SLGFDEPTEQ PVRKNKMASN IFGTPEENQA SWAKSAGAKS SGGREDLESS GLQRRNSSEA SSGDFLDLKG EGDIHENVDT DLPGSLGQSE EKPVPAAPVP SPVAPAPVPS RRNPPGGKSS LVLG

Réactivité croisée: Humain

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 1-154 of human HN1 (NP_057269.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur HN1

Antigène: HN1 (Hematological and Neurological Expressed 1 (HN1))

Autre désignation: HN1

Sujet: Modulates negatively AKT-mediated GSK3B signaling. Induces CTNNB1 'Ser-33' phosphorylation and degradation through the suppression of the inhibitory 'Ser-9' phosphorylation of GSK3B, which represses the function of the APC:CTNNB1:GSK3B complex and the interaction with CDH1/E-cadherin in adherent junctions. Plays a role in the regulation of cell cycle and cell adhesion. Has an inhibitory role on AR-signaling pathway through the induction of receptor proteosomal degradation.,JPT1,ARM2,HN1,HN1A,Cell Biology & Developmental Biology,HN1

Poids moléculaire: 11kDa/16kDa/19kDa

ID gène: 51155

UniProt: Q9UK76