IBTK anticorps (AA 900-1200)

N° du produit ABIN7267871

L’anticorps Lapin Polyclonal anti-IBTK a été validé pour WB. Il convient pour détecter IBTK dans des échantillons de Humain.

Aperçu rapide pour IBTK anticorps (AA 900-1200) (ABIN7267871)

Antigène: IBTK (Inhibitor of Bruton Agammaglobulinemia Tyrosine Kinase (IBTK))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IBTK est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-IBTK anticorps

Épitope: AA 900-1200

Fonction: IBTK Rabbit pAb

Séquence: GLNMAALLEA RSLDVLSDGV LKDLSEFYRK MIPAMDRRVI TPYQDGPDIS YLEVEDGDIF LKEEINMEQN HSETMFKKAK TKAKKKPRKR SDSSGGYNLS DIIQSPSSTG LLKSGKTNSV ESLPELLTSD SEGSYAGVGS PRDLQSPDFT TGFHSDKIEA KVKPYVNGTS PVYSREDLKP WEKSPILKIS APQPIPSNRI DTTSSASWVA GSFSPVSPPV VDLRTIMEIE ESRQKCGATP KSHLGKTVSH GVKLSQKQRK MIALTTKENN SGMNSMETVL FTPSKAPKPV NAWASSLHSV S

Réactivité croisée: Humain

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 900-1200 of human IBTK (NP_056340.2).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur IBTK

Antigène: IBTK (Inhibitor of Bruton Agammaglobulinemia Tyrosine Kinase (IBTK))

Autre désignation: IBTK

Sujet: Bruton tyrosine kinase (BTK) is a protein tyrosine kinase that is expressed in B cells, macrophages, and neutrophils. The protein encoded by this gene binds to BTK and downregulates BTK's kinase activity. In addition, the encoded protein disrupts BTK-mediated calcium mobilization and negatively regulates the activation of nuclear factor-kappa-B-driven transcription. This gene has a pseudogene on chromosome 18. Alternative splicing results in multiple transcript variants encoding distinct isoforms.,IBTK,BTBD26,BTKI,Signal Transduction,Kinase,IBTK

Poids moléculaire: 26kDa/133kDa/150kDa

ID gène: 25998

UniProt: Q9P2D0