ILF2 anticorps
Aperçu rapide pour ILF2 anticorps (ABIN7268007)
Antigène
Voir toutes ILF2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
-
-
Fonction
- ILF2 Rabbit mAb
-
Réactivité croisée
- Humain, Souris, Rat
-
Attributs du produit
- Monoclonal Antibodies
-
Purification
- Affinity purification
-
Immunogène
- A synthesized peptide derived from human ILF2
-
Isotype
- IgG
-
-
-
-
Indications d'application
- WB,1:500 - 1:2000,IHC,1:50 - 1:200
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Buffer
- PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
-
Agent conservateur
- Sodium azide
-
Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Stock
- -20 °C
-
Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
-
-
- ILF2 (Interleukin Enhancer Binding Factor 2, 45kDa (ILF2))
-
Autre désignation
- ILF2
-
Sujet
- The protein encoded by this gene is a transcription factor required for T-cell expression of the interleukin 2 gene. It also binds RNA and is an essential component for encapsidation and protein priming of hepatitis B viral polymerase. The encoded 45 kDa protein (NF45, ILF2) forms a complex with the 90 kDa interleukin enhancer-binding factor 3 (NF90, ILF3), and this complex has been shown to affect the redistribution of nuclear mRNA to the cytoplasm, to repair DNA breaks by nonhomologous end joining, and to negatively regulate the microRNA processing pathway. Knockdown of NF45 or NF90 protein retards cell growth, possibly by inhibition of mRNA stabilization. Alternative splicing results in multiple transcript variants. Related pseudogenes have been found on chromosomes 3 and 14. [provided by RefSeq, Dec 2014],NF45, PRO3063,Epigenetics & Nuclear Signaling,RNA Binding,Transcription Factors,ILF2
-
Poids moléculaire
- 43kDa
-
ID gène
- 3608
-
UniProt
- Q12905
Antigène
-