JARID2 anticorps
Aperçu rapide pour JARID2 anticorps (ABIN7268047)
Antigène
Voir toutes JARID2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Fonction
- JARID2 Rabbit mAb
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Réactivité croisée
- Humain, Souris, Rat
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Attributs du produit
- Monoclonal Antibodies
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Purification
- Affinity purification
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Immunogène
- A synthesized peptide derived from human JARID2
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Isotype
- IgG
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Indications d'application
- WB,1:500 - 1:2000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- JARID2 (Jumonji, AT Rich Interactive Domain 2 (JARID2))
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Autre désignation
- JARID2
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Sujet
- This gene encodes a Jumonji- and AT-rich interaction domain (ARID)-domain-containing protein. The encoded protein is a DNA-binding protein that functions as a transcriptional repressor. This protein interacts with the Polycomb repressive complex 2 (PRC2) which plays an essential role in regulating gene expression during embryonic development. This protein facilitates the recruitment of the PRC2 complex to target genes. Alternate splicing results in multiple transcript variants. Mutations in this gene are associated with chronic myeloid malignancies. [provided by RefSeq, May 2012],JMJ,Epigenetics & Nuclear Signaling,Neuroscience,JARID2
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Poids moléculaire
- 139kDa
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ID gène
- 3720
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UniProt
- Q92833
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Pathways
- Chromatin Binding
Antigène
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