KAT6B anticorps (AA 400-500)

N° du produit ABIN7268062

Cet anticorps Lapin Polyclonal détecte spécifiquement KAT6B dans WB. Il présente une réactivité envers Humain.

Aperçu rapide pour KAT6B anticorps (AA 400-500) (ABIN7268062)

Antigène: KAT6B (K(lysine) Acetyltransferase 6B (KAT6B))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KAT6B est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-KAT6B anticorps

Épitope: AA 400-500

Fonction: KAT6B Rabbit pAb

Séquence: DLDVFKQAQE LSWEKIECES GVEDCGRYPS VIEFGKYEIQ TWYSSPYPQE YARLPKLYLC EFCLKYMKSK NILLRHSKKC GWFHPPANEI YRRKDLSVFE V

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: A synthetic peptide corresponding to a sequence within amino acids 400-500 of human KAT6B (NP_001243398.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur KAT6B

Antigène: KAT6B (K(lysine) Acetyltransferase 6B (KAT6B))

Autre désignation: KAT6B

Sujet: The protein encoded by this gene is a histone acetyltransferase and component of the MOZ/MORF protein complex. In addition to its acetyltransferase activity, the encoded protein has transcriptional activation activity in its N-terminal end and transcriptional repression activity in its C-terminal end. This protein is necessary for RUNX2-dependent transcriptional activation and could be involved in brain development. Mutations have been found in patients with genitopatellar syndrome. A translocation of this gene and the CREBBP gene results in acute myeloid leukemias. Three transcript variants encoding different isoforms have been found for this gene.,KAT6B,GTPTS,MORF,MOZ2,MYST4,ZC2HC6B,qkf,querkopf,Epigenetics & Nuclear Signaling,Chromatin Modifying Enzymes,Acetylation,KAT6B

ID gène: 23522

UniProt: Q8WYB5