KIF5B anticorps (AA 650-770)

N° du produit ABIN7268136

Cet anticorps anti-KIF5B est un anticorps Lapin Polyclonal détectant KIF5B dans WB, IHC et IF. Adapté pour Humain.

Aperçu rapide pour KIF5B anticorps (AA 650-770) (ABIN7268136)

Antigène: KIF5B (Kinesin Family Member 5B (KIF5B))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KIF5B est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-KIF5B anticorps

Épitope: AA 650-770

Fonction: KIF5B Rabbit pAb

Séquence: LQNVEQKKRQ LEESVDALSE ELVQLRAQEK VHEMEKEHLN KVQTANEVKQ AVEQQIQSHR ETHQKQISSL RDEVEAKAKL ITDLQDQNQK MMLEQERLRV EHEKLKATDQ EKSRKLHELT V

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 650-770 of human KIF5B (NP_004512.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IHC,1:50 - 1:100,IF,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur KIF5B

Antigène: KIF5B (Kinesin Family Member 5B (KIF5B))

Autre désignation: KIF5B

Sujet: Microtubule-dependent motor required for normal distribution of mitochondria and lysosomes. Can induce formation of neurite-like membrane protrusions in non-neuronal cells in a ZFYVE27-dependent manner (By similarity. Regulates centrosome and nuclear positioning during mitotic entry. During the G2 phase of the cell cycle in a BICD2-dependent manner, antagonizes dynein function and drives the separation of nuclei and centrosomes. Required for anterograde axonal transportation of MAPK8IP3/JIP3 which is essential for MAPK8IP3/JIP3 function in axon elongation (By similarity. Through binding with PLEKHM2 and ARL8B, directs lysosome movement toward microtubule plus ends (Probable. Involved in NK cell-mediated cytotoxicity. Drives the polarization of cytolytic granules and microtubule-organizing centers (MTOCs toward the immune synapse between effector NK lymphocytes and target cells.,KIF5B,HEL-S-61,KINH,KNS,KNS1,UKHC,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Motor Proteins,KIF5B

Poids moléculaire: 109kDa

ID gène: 3799

UniProt: P33176

Pathways: Peptide Hormone Metabolism, Ribonucleoprotein Complex Subunit Organization