LAMa4 anticorps (AA 1-100)

N° du produit ABIN7268183

L’anticorps Lapin Polyclonal anti-LAMa4 a été validé pour WB. Il convient pour détecter LAMa4 dans des échantillons de Humain.

Aperçu rapide pour LAMa4 anticorps (AA 1-100) (ABIN7268183)

Antigène: LAMa4 (Laminin, alpha 4 (LAMa4))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LAMa4 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-LAMa4 anticorps

Épitope: AA 1-100

Fonction: LAMA4 Rabbit pAb

Séquence: MALSSAWRSV LPLWLLWSAA CSRAASGDDN AFPFDIEGSS AVGRQDPPET SEPRVALGRL PPAAEVQCPC HCHPAGAPAP PRAVPHSSFS LSPPLSSPQC

Réactivité croisée: Humain

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: A synthetic peptide corresponding to a sequence within amino acids 1-100 of human LAMA4 (NP_001098678.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:200 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur LAMa4

Antigène: LAMa4 (Laminin, alpha 4 (LAMa4))

Autre désignation: LAMA4

Sujet: Laminins, a family of extracellular matrix glycoproteins, are the major noncollagenous constituent of basement membranes. They have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis. Laminins are composed of 3 non identical chains: laminin alpha, beta and gamma (formerly A, B1, and B2, respectively) and they form a cruciform structure consisting of 3 short arms, each formed by a different chain, and a long arm composed of all 3 chains. Each laminin chain is a multidomain protein encoded by a distinct gene. Several isoforms of each chain have been described. Different alpha, beta and gamma chain isomers combine to give rise to different heterotrimeric laminin isoforms which are designated by Arabic numerals in the order of their discovery, i.e. alpha1beta1gamma1 heterotrimer is laminin 1. This gene encodes the alpha chain isoform laminin, alpha 4. The domain structure of alpha 4 is similar to that of alpha 3, both of which resemble truncated versions of alpha 1 and alpha 2, in that approximately 1,200 residues at the N-terminus (domains IV, V and VI) have been lost. Laminin, alpha 4 contains the C-terminal G domain which distinguishes all alpha chains from the beta and gamma chains. The RNA analysis from adult and fetal tissues revealed developmental regulation of expression, Tissue-specific utilization of alternative polyA-signal has been described in literature.,LAMA4,CMD1JJ,LAMA3,LAMA4*-1,Signal Transduction,Cell Biology & Developmental Biology,Cell Adhesion,Cytoskeleton,Extracellular Matrix,Neuroscience,LAMA4

Poids moléculaire: 12kDa/201kDa/202kDa

ID gène: 3910

UniProt: Q16363

Pathways: Brown Fat Cell Differentiation