LRRFIP2 anticorps (AA 150-340)

N° du produit ABIN7268214

Détail du produit anti-LRRFIP2 anticorps

Antigène: LRRFIP2 (Leucine Rich Repeat (In FLII) Interacting Protein 2 (LRRFIP2))

Épitope: AA 150-340

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LRRFIP2 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Fonction: LRRFIP2 Rabbit pAb

Séquence: VIEEQEEQMA EFYRENEEKS KELERQKHMC SVLQHKMEEL KEGLRQRDEL IEKHGLVIIP DGTPNGDVSH EPVAGAITVV SQEAAQVLES AGEGPLDVRL RKLAGEKEEL LSQIRKLKLQ LEEERQKCSR NDGTVGDLAG LQNGSDLQFI EMQRDANRQI SEYKFKLSKA EQDITTLEQS ISRLEGQVLR Y

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 150-340 of human LRRFIP2 (NP_060194.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IF,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur LRRFIP2

Antigène: LRRFIP2 (Leucine Rich Repeat (In FLII) Interacting Protein 2 (LRRFIP2))

Autre désignation: LRRFIP2 (LRRFIP2 Produits)

Synonymes: anticorps HUFI-2, anticorps 5133400F20Rik, anticorps AI850587, anticorps wu:fj34c02, anticorps zgc:113956, anticorps zgc:63771, anticorps LRR binding FLII interacting protein 2, anticorps leucine rich repeat (in FLII) interacting protein 2, anticorps leucine rich repeat (in FLII) interacting protein 2 L homeolog, anticorps LRRFIP2, anticorps Lrrfip2, anticorps lrrfip2, anticorps lrrfip2.L

Sujet: The protein encoded by this gene, along with MYD88, binds to the cytosolic tail of toll-like receptor 4 (TLR4), which results in activation of nuclear factor kappa B signaling. The ubiquitin-like protein FAT10 prevents the interaction of the encoded protein and TLR4, thereby inactivating the nuclear factor kappa B signaling pathway. In addition, this protein can downregulate the NLRP3 inflammasome by recruiting the caspase-1 inhibitor Flightless-I to the inflammasome complex.,LRRFIP2,HUFI-2,Epigenetics & Nuclear Signaling,Signal Transduction,Immunology & Inflammation,Toll-like Receptor Signaling Pathway,Cell Intrinsic Innate Immunity Signaling Pathway,TLR Signaling,Stem Cells,LRRFIP2

ID gène: 9209

UniProt: Q9Y608