LILRB3 anticorps (AA 400-500)
Aperçu rapide pour LILRB3 anticorps (AA 400-500) (ABIN7268239)
Antigène
Voir toutes LILRB3 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 400-500
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Fonction
- LILRB3 Rabbit pAb
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Séquence
- RSSNPHLLSF PSEPLELMVS GHSGGSSLPP TGPPSTPGGP EDQPLNPPGS GPQNGLGRYL EVLIGVSVAF VLLLFLLLFL LLLRQRHSKH RTSDQRKTDF Q
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Réactivité croisée
- Humain, Souris
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Attributs du produit
- Polyclonal Antibodies
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Purification
- Affinity purification
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Immunogène
- A synthetic peptide corresponding to a sequence within amino acids 400-500 of human LILRB3 (NP_001307889.1).
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Isotype
- IgG
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Indications d'application
- WB,1:500 - 1:2000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- LILRB3 (Leukocyte Immunoglobulin-Like Receptor B3 (LILRB3))
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Autre désignation
- LILRB3
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Sujet
- This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene.,LILRB3,CD85A,HL9,ILT-5,ILT5,LILRA6,LIR-3,LIR3,PIR-B,PIRB,Immunology & Inflammation,CD markers,B Cell Receptor Signaling Pathway,LILRB3
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Poids moléculaire
- 69kDa/71kDa
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ID gène
- 11025
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UniProt
- O75022
Antigène
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