MSL1 anticorps (AA 210-300)

N° du produit ABIN7268383

Détail du produit anti-MSL1 anticorps

Antigène: MSL1 (Male-Specific Lethal 1 Homolog (MSL1))

Épitope: AA 210-300

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MSL1 est non-conjugé

Application: Western Blotting (WB)

Fonction: MSL1 Rabbit pAb

Séquence: LAVPSWRDHS VEPLRDPNPS DLLENLDDSV FSKRHAKLEL DEKRRKRWDI QRIREQRILQ RLQLRMYKKK GIQESEPEVT SFFPEPDDVE S

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 210-300 of human MSL1 (NP_001012241).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur MSL1

Antigène: MSL1 (Male-Specific Lethal 1 Homolog (MSL1))

Autre désignation: MSL1 (MSL1 Produits)

Synonymes: anticorps MSL-1, anticorps hMSL1, anticorps 2810017F12Rik, anticorps 4121402D02Rik, anticorps 4930463F05Rik, anticorps AA682082, anticorps Msl-1, anticorps male specific lethal 1 homolog, anticorps male-specific lethal 1 homolog (Drosophila), anticorps MSL1, anticorps Msl1

Sujet: Component of histone acetyltransferase complex responsible for the majority of histone H4 acetylation at 'Lys-16' (H4K16ac which is implicated in the formation of higher-order chromatin structure. Greatly enhances MSL2 E3 ubiquitin ligase activity, promoting monoubiquitination of histone H2B at 'Lys-34' (H2BK34Ub. This modification in turn stimulates histone H3 methylation at 'Lys-4' (H3K4me and 'Lys-79' (H3K79me and leads to gene activation, including that of HOXA9 and MEIS1. In the MSL complex, acts as a scaffold to tether MSL3 and KAT8 together for enzymatic activity regulation.,MSL-1,hMSL1,MSL1,Epigenetics & Nuclear Signaling,Histones,MSL1

ID gène: 339287

UniProt: Q68DK7