MMP25 anticorps (AA 350-540)

N° du produit ABIN7268422

Cet anticorps Lapin Polyclonal détecte spécifiquement MMP25 dans WB, IHC et IF. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour MMP25 anticorps (AA 350-540) (ABIN7268422)

Antigène: MMP25 (Matrix Metallopeptidase 25 (MMP25))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MMP25 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-MMP25 anticorps

Épitope: AA 350-540

Fonction: MMP25 Rabbit pAb

Séquence: SPRPARLHRF WEGLPAQVRV VQAAYARHRD GRILLFSGPQ FWVFQDRQLE GGARPLTELG LPPGEEVDAV FSWPQNGKTY LVRGRQYWRY DEAAARPDPG YPRDLSLWEG APPSPDDVTV SNAGDTYFFK GAHYWRFPKN SIKTEPDAPQ PMGPNWLDCP APSSGPRAPR PPKATPVSET CDCQCELNQA A

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 350-540 of human MMP25 (NP_071913.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur MMP25

Antigène: MMP25 (Matrix Metallopeptidase 25 (MMP25))

Autre désignation: MMP25

Sujet: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the protein encoded by this gene is a member of the membrane-type MMP (MT-MMP) subfamily, attached to the plasma membrane via a glycosylphosphatidyl inositol anchor. In response to bacterial infection or inflammation, the encoded protein is thought to inactivate alpha-1 proteinase inhibitor, a major tissue protectant against proteolytic enzymes released by activated neutrophils, facilitating the transendothelial migration of neutrophils to inflammatory sites. The encoded protein may also play a role in tumor invasion and metastasis through activation of MMP2. The gene has previously been referred to as MMP20 but has been renamed MMP25.,MMP25,MMP-25,MMP20,MMP20A,MMPL1,MT-MMP 6,MT-MMP6,MT6-MMP,MT6MMP,MTMMP6,Cancer,Invasion and Metastasis,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Extracellular Matrix,MMPs,Ubiquitin,MMP25

Poids moléculaire: 62kDa

ID gène: 64386

UniProt: Q9NPA2