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MBD3 anticorps

L’anticorps Lapin Monoclonal anti-MBD3 a été validé pour WB et IHC. Il convient pour détecter MBD3 dans des échantillons de Humain.
N° du produit ABIN7268492

Aperçu rapide pour MBD3 anticorps (ABIN7268492)

Antigène

Voir toutes MBD3 Anticorps
MBD3 (Methyl-CpG Binding Domain Protein 3 (MBD3))

Reactivité

  • 66
  • 30
  • 17
  • 3
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
Humain

Hôte

  • 56
  • 8
  • 2
Lapin

Clonalité

  • 52
  • 14
Monoclonal

Conjugué

  • 43
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
Cet anticorp MBD3 est non-conjugé

Application

  • 42
  • 25
  • 11
  • 8
  • 6
  • 4
  • 4
  • 3
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC)
  • Fonction

    MBD3 Rabbit mAb

     Réactivité croisée

    Humain, Souris, Rat

    Attributs du produit

    Monoclonal Antibodies

    Purification

    Affinity purification

    Immunogène

    A synthesized peptide derived from human MBD3

    Isotype

    IgG
  • Indications d'application

    WB,1:500 - 1:2000,IHC,1:50 - 1:200

    Restrictions

    For Research Use only
  • Format

    Liquid

    Buffer

    PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Stock

    -20 °C

    Stockage commentaire

    Store at -20°C. Avoid freeze / thaw cycles.
  • Antigène

    MBD3 (Methyl-CpG Binding Domain Protein 3 (MBD3))

    Autre désignation

    MBD3

    Sujet

    DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. This gene belongs to a family of nuclear proteins which are characterized by the presence of a methyl-CpG binding domain (MBD). The encoded protein is a subunit of the NuRD, a multisubunit complex containing nucleosome remodeling and histone deacetylase activities. Unlike the other family members, the encoded protein is not capable of binding to methylated DNA. The protein mediates the association of metastasis-associated protein 2 with the core histone deacetylase complex. Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, Jul 2013],MBD3, methyl-CpG-binding domain protein 3,Epigenetics & Nuclear Signaling,MBD3

    Poids moléculaire

    33kDa

    ID gène

    53615

    UniProt

    O95983

    Pathways

    Chromatin Binding
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