MRPL43
Reactivité: Humain, Souris, Rat, Boeuf (Vache), Cobaye, Cheval
WB
Hôte: Lapin
Polyclonal
unconjugated
Indications d'application
WB,1:500 - 1:2000,IF,1:50 - 1:200
Restrictions
For Research Use only
Format
Liquid
Buffer
PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
-20 °C
Stockage commentaire
Store at -20°C. Avoid freeze / thaw cycles.
Antigène
MRPL43
(Mitochondrial Ribosomal Protein L43 (MRPL43))
Autre désignation
MRPL43
Sujet
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75 % protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. This gene and the gene for a semaphorin class 4 protein (SEMA4G) overlap at map location 10q24.31 and are transcribed in opposite directions. Sequence analysis identified multiple transcript variants encoding at least four different protein isoforms. [provided by RefSeq, Jul 2008],L43mt,MRP-L43,bMRP36a,MRPL43,Epigenetics & Nuclear Signaling,RNA Binding,Endocrine & Metabolism,Mitochondrial metabolism,Mitochondrial markers,Mitochondrial translation,MRPL43