GNPTAB anticorps (AA 42-350)

N° du produit ABIN7268770

Cet anticorps Lapin Polyclonal détecte spécifiquement GNPTAB dans WB. Il présente une réactivité envers Humain.

Aperçu rapide pour GNPTAB anticorps (AA 42-350) (ABIN7268770)

Antigène: GNPTAB (N-Acetylglucosamine-1-Phosphate Transferase, alpha and beta Subunits (GNPTAB))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GNPTAB est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-GNPTAB anticorps

Épitope: AA 42-350

Fonction: GNPTAB Rabbit pAb

Séquence: LEWSRDQYHV LFDSYRDNIA GKSFQNRLCL PMPIDVVYTW VNGTDLELLK ELQQVREQME EEQKAMREIL GKNTTEPTKK SEKQLECLLT HCIKVPMLVL DPALPANITL KDLPSLYPSF HSASDIFNVA KPKNPSTNVS VVVFDSTKDV EDAHSGLLKG NSRQTVWRGY LTTDKEVPGL VLMQDLAFLS GFPPTFKETN QLKTKLPENL SSKVKLLQLY SEASVALLKL NNPKDFQELN KQTKKNMTID GKELTISPAY LLWDLSAISQ SKQDEDISAS RFEDNEELRY SLRSIERHAP WVRNIFIVT

Réactivité croisée: Humain

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 42-350 of human GNPTAB (NP_077288.2).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur GNPTAB

Antigène: GNPTAB (N-Acetylglucosamine-1-Phosphate Transferase, alpha and beta Subunits (GNPTAB))

Autre désignation: GNPTAB

Sujet: This gene encodes two of three subunit types of the membrane-bound enzyme N-acetylglucosamine-1-phosphotransferase, a heterohexameric complex composed of two alpha, two beta, and two gamma subunits. The encoded protein is proteolytically cleaved at the Lys928-Asp929 bond to yield mature alpha and beta polypeptides while the gamma subunits are the product of a distinct gene (GeneID 84572). In the Golgi apparatus, the heterohexameric complex catalyzes the first step in the synthesis of mannose 6-phosphate recognition markers on certain oligosaccharides of newly synthesized lysosomal enzymes. These recognition markers are essential for appropriate trafficking of lysosomal enzymes. Mutations in this gene have been associated with both mucolipidosis II and mucolipidosis IIIA.,GNPTAB,GNPTA,ICD,Cancer,Signal Transduction,Endocrine & Metabolism,GNPTAB

Poids moléculaire: 55kDa/143kDa

ID gène: 79158

UniProt: Q3T906