NQO1 anticorps
Aperçu rapide pour NQO1 anticorps (ABIN7268795)
Antigène
Voir toutes NQO1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Fonction
- NQO1 Rabbit mAb
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Réactivité croisée
- Humain, Souris, Rat
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Attributs du produit
- Monoclonal Antibodies
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Purification
- Affinity purification
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Immunogène
- A synthesized peptide derived from human NQO1.
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Isotype
- IgG
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Indications d'application
- WB,1:500 - 1:2000,IHC,1:50 - 1:200,IP,1:50 - 1:200
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- NQO1 (NAD(P)H Dehydrogenase, Quinone 1 (NQO1))
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Autre désignation
- NQO1
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Sujet
- This gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. This FAD-binding protein forms homodimers and reduces quinones to hydroquinones. This protein's enzymatic activity prevents the one electron reduction of quinones that results in the production of radical species. Mutations in this gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer. Altered expression of this protein has been seen in many tumors and is also associated with Alzheimer's disease (AD). Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008],DHQU;DIA4;DTD;NMOR1;NMORI;QR1;NQO1,Cancer,Drug metabolism,Endocrine & Metabolism,Epigenetics & Nuclear Signaling,RNA Binding,Signal Transduction,NQO1
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Poids moléculaire
- 31kDa
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ID gène
- 1728
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UniProt
- P15559
Antigène
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