Neuropilin 1 anticorps (AA 21-250)
Aperçu rapide pour Neuropilin 1 anticorps (AA 21-250) (ABIN7268892)
Antigène
Voir toutes Neuropilin 1 (NRP1) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 21-250
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Fonction
- Neuropilin-1 (NRP1) Rabbit pAb
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Séquence
- AFRNDKCGDT IKIESPGYLT SPGYPHSYHP SEKCEWLIQA PDPYQRIMIN FNPHFDLEDR DCKYDYVEVF DGENENGHFR GKFCGKIAPP PVVSSGPFLF IKFVSDYETH GAGFSIRYEI FKRGPECSQN YTTPSGVIKS PGFPEKYPNS LECTYIVFAP KMSEIILEFE SFDLEPDSNP PGGMFCRYDR LEIWDGFPDV GPHIGRYCGQ KTPGRIRSSS GILSMVFYTD
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Réactivité croisée
- Humain, Souris, Rat
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Attributs du produit
- Polyclonal Antibodies
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Purification
- Affinity purification
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Immunogène
- Recombinant fusion protein containing a sequence corresponding to amino acids 21-250 of human Neuropilin-1 (Neuropilin-1 (NRP1)) (NP_001019800.1).
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Isotype
- IgG
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Indications d'application
- WB,1:500 - 1:3000,IF,1:50 - 1:200
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- Neuropilin 1 (NRP1)
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Autre désignation
- NRP1
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Sujet
- This gene encodes one of two neuropilins, which contain specific protein domains which allow them to participate in several different types of signaling pathways that control cell migration. Neuropilins contain a large N-terminal extracellular domain, made up of complement-binding, coagulation factor V/VIII, and meprin domains. These proteins also contains a short membrane-spanning domain and a small cytoplasmic domain. Neuropilins bind many ligands and various types of co-receptors, they affect cell survival, migration, and attraction. Some of the ligands and co-receptors bound by neuropilins are vascular endothelial growth factor (VEGF) and semaphorin family members. Several alternatively spliced transcript variants that encode different protein isoforms have been described for this gene.,BDCA4,CD304,NP1,NRP,VEGF165R,Neuropilin-1,NRP1,Cell Biology & Developmental Biology,Growth factor,VEGF,VEGF Receptors,Immunology & Inflammation,CD markers,Neuroscience,Stem Cells,Cardiovascular,Angiogenesis,NRP1
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Poids moléculaire
- 68kDa/71kDa/103kDa
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ID gène
- 8829
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UniProt
- O14786
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Pathways
- Regulation of Cell Size, Signaling Events mediated by VEGFR1 and VEGFR2, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling, VEGFR1 Specific Signals
Antigène
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