NCAPD2 anticorps

N° du produit ABIN7268948

L’anticorps anti-NCAPD2 Monoclonal Lapin est utilisé pour la détection de NCAPD2 dans des échantillons de Humain. Il a été validé pour WB.

Aperçu rapide pour NCAPD2 anticorps (ABIN7268948)

Antigène: NCAPD2 (Non-SMC Condensin I Complex, Subunit D2 (NCAPD2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp NCAPD2 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-NCAPD2 anticorps

Fonction: CNAP1 Rabbit mAb

Réactivité croisée: Humain, Souris

Attributs du produit: Monoclonal Antibodies

Purification: Affinity purification

Immunogène: A synthesized peptide derived from human CNAP1.

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur NCAPD2

Antigène: NCAPD2 (Non-SMC Condensin I Complex, Subunit D2 (NCAPD2))

Autre désignation: CNAP1

Sujet: Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases. May target the condensin complex to DNA via its C-terminal domain. May promote the resolution of double-strand DNA catenanes (intertwines between sister chromatids. Condensin-mediated compaction likely increases tension in catenated sister chromatids, providing directionality for type II topoisomerase-mediated strand exchanges toward chromatid decatenation. Required for decatenation of non-centromeric ultrafine DNA bridges during anaphase. Early in neurogenesis, may play an essential role to ensure accurate mitotic chromosome condensation in neuron stem cells, ultimately affecting neuron pool and cortex size.,NCAPD2, CAP-D2, CNAP1, hCAP-D2, condensin complex subunit 1,Epigenetics & Nuclear Signaling,Cell Biology & Developmental Biology,Cell Cycle,CNAP1

Poids moléculaire: 150kDa

ID gène: 9918

UniProt: Q15021