NXF1 anticorps (AA 57-356)

N° du produit ABIN7269024

Détail du produit anti-NXF1 anticorps

Antigène: NXF1 (Nuclear RNA Export Factor 1 (NXF1))

Épitope: AA 57-356

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NXF1 est non-conjugé

Application: Western Blotting (WB)

Fonction: NXF1 Rabbit pAb

Séquence: GDVAMSDAQD GPRVRYNPYT TRPNRRGDTW HDRDRIHVTV RRDRAPPERG GAGTSQDGTS KNWFKITIPY GRKYDKAWLL SMIQSKCSVP FTPIEFHYEN TRAQFFVEDA STASALKAVN YKILDRENRR ISIIINSSAP PHTILNELKP EQVEQLKLIM SKRYDGSQQA LDLKGLRSDP DLVAQNIDVV LNRRSCMAAT LRIIEENIPE LLSLNLSNNR LYRLDDMSSI VQKAPNLKIL NLSGNELKSE RELDKIKGLK LEELWLDGNS LCDTFRDQST YIRSVVACVS PPGDLHPLGG

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 57-356 of human NXF1 (NP_001074960.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur NXF1

Antigène: NXF1 (Nuclear RNA Export Factor 1 (NXF1))

Autre désignation: NXF1 (NXF1 Produits)

Synonymes: anticorps im:7156527, anticorps wu:fc12d06, anticorps MGC82224, anticorps NXF1, anticorps tap, anticorps mex67, anticorps MEX67, anticorps TAP, anticorps Mex67, anticorps Mvb1, anticorps Tap, anticorps Mex67h, anticorps nuclear RNA export factor 1, anticorps nuclear RNA export factor 1 S homeolog, anticorps Nuclear RNA export factor 1, anticorps nxf1, anticorps nxf1.S, anticorps NXF1, anticorps LOC100113601, anticorps Tsp_03999, anticorps Nxf1, anticorps nxf-1

Sujet: This gene is one member of a family of nuclear RNA export factor genes. Common domain features of this family are a noncanonical RNP-type RNA-binding domain (RBD), 4 leucine-rich repeats (LRRs), a nuclear transport factor 2 (NTF2)-like domain that allows heterodimerization with NTF2-related export protein-1 (NXT1), and a ubiquitin-associated domain that mediates interactions with nucleoporins. The LRRs and NTF2-like domains are required for export activity. Alternative splicing seems to be a common mechanism in this gene family. The encoded protein of this gene shuttles between the nucleus and the cytoplasm and binds in vivo to poly(A)+ RNA. It is the vertebrate homologue of the yeast protein Mex67p. The encoded protein overcomes the mRNA export block caused by the presence of saturating amounts of CTE (constitutive transport element) RNA of type D retroviruses. Alternative splicing results in multiple transcript variants.,NXF1,MEX67,TAP,Epigenetics & Nuclear Signaling,RNA Binding,NXF1

Poids moléculaire: 40kDa/70kDa

ID gène: 10482

UniProt: Q9UBU9