Mu Opioid Receptor 1 anticorps (C-Term)

N° du produit ABIN7269101

L’anticorps Lapin Polyclonal anti-Mu Opioid Receptor 1 a été validé pour WB, IHC et IF. Il convient pour détecter Mu Opioid Receptor 1 dans des échantillons de Humain.

Aperçu rapide pour Mu Opioid Receptor 1 anticorps (C-Term) (ABIN7269101)

Antigène: Mu Opioid Receptor 1 (OPRM1) (Opioid Receptor, mu 1 (OPRM1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Mu Opioid Receptor 1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-Mu Opioid Receptor 1 anticorps

Épitope: C-Term

Fonction: Mu Opioid Receptor(MOR) Rabbit pAb

Séquence: IYVIIKALVT IPETTFQTVS WHFCIALGYT NSCLNPVLYA FLDENFKRCF REFCIPTSSN IEQQNSTRIR QNTRDHPSTA NTVDRTNHQL ENLEAETAPL P

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: A synthetic peptide corresponding to a sequence within amino acids 300 to the C-terminus of human Mu Opioid Receptor(MOR) (NP_000905.3).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur Mu Opioid Receptor 1

Antigène: Mu Opioid Receptor 1 (OPRM1) (Opioid Receptor, mu 1 (OPRM1))

Autre désignation: OPRM1

Sujet: This gene encodes one of at least three opioid receptors in humans; the mu opioid receptor (MOR). The MOR is the principal target of endogenous opioid peptides and opioid analgesic agents such as beta-endorphin and enkephalins. The MOR also has an important role in dependence to other drugs of abuse, such as nicotine, cocaine, and alcohol via its modulation of the dopamine system. The NM_001008503.2:c.118A>G allele has been associated with opioid and alcohol addiction and variations in pain sensitivity but evidence for it having a causal role is conflicting. Multiple transcript variants encoding different isoforms have been found for this gene. Though the canonical MOR belongs to the superfamily of 7-transmembrane-spanning G-protein-coupled receptors some isoforms of this gene have only 6 transmembrane domains.,OPRM1;LMOR;M-OR-1;MOP;MOR;MOR1;OPRM,Signal Transduction,G protein signaling,G-Protein-Coupled Receptors(GPCR),Cell Biology & Developmental Biology,Neuroscience,OPRM1

Poids moléculaire: 10-20kDa/33-55kDa

ID gène: 4988

UniProt: P35372

Pathways: cAMP Metabolic Process, Synaptic Membrane