OTX2 anticorps
Aperçu rapide pour OTX2 anticorps (ABIN7269116)
Antigène
Voir toutes OTX2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Fonction
- OTX2 Rabbit mAb
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Réactivité croisée
- Humain, Souris, Rat
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Attributs du produit
- Monoclonal Antibodies
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Purification
- Affinity purification
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Immunogène
- A synthesized peptide derived from human OTX2
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Isotype
- IgG
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Indications d'application
- WB,1:500 - 1:2000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- OTX2 (Orthodenticle Homeobox 2 (OTX2))
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Autre désignation
- OTX2
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Sujet
- This gene encodes a member of the bicoid subfamily of homeodomain-containing transcription factors. The encoded protein acts as a transcription factor and plays a role in brain, craniofacial, and sensory organ development. The encoded protein also influences the proliferation and differentiation of dopaminergic neuronal progenitor cells during mitosis. Mutations in this gene cause syndromic microphthalmia 5 (MCOPS5) and combined pituitary hormone deficiency 6 (CPHD6). This gene is also suspected of having an oncogenic role in medulloblastoma. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Pseudogenes of this gene are known to exist on chromosomes two and nine. [provided by RefSeq, Jul 2012],CPHD6, MCOPS5,Cell Biology & Developmental Biology,Epigenetics & Nuclear Signaling,Neuroscience,Stem Cells,Transcription Factors,OTX2
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Poids moléculaire
- 32kDa
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ID gène
- 5015
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UniProt
- P32243
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Pathways
- Dopaminergic Neurogenesis
Antigène
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